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Anal transitional zone adenocarcinoma following restorative proctocolectomy for ulcerative colitis : case report and review of literature

Journal Volume 72 - 2009
Issue Fasc.4 - Case reports
Author(s) L. Panier-Suffat, M. Marracino, A. Resegotti, M. Astegiano, A. Giustetto, M. Garino, R. Pellicano, G. Fronda
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(1) 7th Department of Surgery ; (2) Department of Gastro-Hepatology, S.Giovanni Battista (Molinette) Hospital, Turin, Italy.

Conservative proctocolectomy with ileal pouch-anal anastomosis (IPAA) has become the intervention of choice for severe ulcerative colitis (UC) requiring surgery. Sporadically, the occurrence of carcinoma arising in or near the ileo-anal pouch after IPAA for UC has been reported. This issue is of utmost importance as an endoscopic follow-up is mandatory also after the operation. The present paper reports a case of cancer which developed four years after proctocolectomy with IPAA in a young man suffering from UC. Moreover, the authors provide update (PubMed research) by literature review on this issue. (Acta gastroenterol. belg., 2009, 72, 441-443).

© Acta Gastro-Enterologica Belgica.
PMID 20163039